000 02913cam a2200313 i 4500
001 18653928
003 OSt
005 20220517165757.0
008 150610t20162016njua b 001 0 eng c
010 _a 2015020801
020 _a9781118771600 (cloth)
020 _a1118771605 (cloth)
040 _aWaSeSS/DLC
_beng
_cWaSeSS
_erda
_dDLC
042 _apcc
050 0 0 _aRS403
_b.S62 2016
082 0 0 _a615.1/9
_223
245 0 0 _aSmall molecule medicinal chemistry :
_bstrategies and technologies /
_cedited by Werngard Czechtizky, Peter Hamley.
300 _axiv, 509 pages :
_billustrations (some color) ;
_c24 cm
504 _aIncludes bibliographical references and index.
505 0 _aElements for the development of strategies for compound library enhancement / Edgar Jacoby -- The European lead factory / Christopher Kallus, Jörg Hüser, Philip S. Jones, Adam Nelson -- Access to compound collections : new business models for compound acquisition and sharing / Peter ten Holte -- New advances in diversity-oriented synthesis / Warren R. J. D. Galloway, Jamie E. Stokes, David R. Spring -- Solid-phase combinatorial chemistry : ready for a revival? / Marcel Patek, Martin Smrcina, Eric Wegrzyniak, Victor Nikolaev, Andres Mariscal -- Recent advances in multicomponent reaction chemistry : applications in small molecule drug discovery / Christopher Hulme, Muhammad Ayaz, Guillermo Martinez-Ariza, Federico Medda, Arthur Shaw -- Computational techniques to support hit triage / Douglas B. Kitchen, Hélène Y. Decornez -- Fragment-based drug discovery / Jean-Paul Renaud, Thomas Neumann and Luc Van Hijfte -- Virtual screening / Karl-Heinz Baringhaus, Gerhard Hessler -- Phenotypic screening / Michelle Palmer -- Advances in the understanding of drug properties in medicinal chemistry / Peter Hamley, Patrick Jimonet -- Recent developments in automated solution phase library production / Thomas C. Maier, Werngard Czechtizky -- Adme profiling : an introduction for the medicinal chemist / Katharina Mertsch, Martin Will, Werngard Czechtizky, Niels Griesang, Alexander Marker, Jacob Olsen -- The role of natural products in drug discovery : examples of marketed drugs / Lars Ole Haustedt and Karsten Siems -- Peptidomimetics of a-helical and b-strand protein binding epitopes / Nina Bionda, Rudi Fasan -- In vivo imaging of drug action / Oliver Plettenburg, Matthias Löhn.
650 0 _aPharmaceutical chemistry.
_916396
650 0 _aDrug development.
_916397
700 1 _aCzechtizky, Werngard,
_eeditor.
_916398
700 1 _aHamley, Peter,
_eeditor.
_916399
776 0 8 _iOnline version:
_tSmall molecule medicinal chemistry
_dHoboken, New Jersey : John Wiley & Sons, 2015
_z9781118771570
_w(DLC) 2015023571
906 _a7
_bcbc
_corignew
_d1
_eecip
_f20
_gy-gencatlg
942 _2ddc
_cBK
999 _c185749
_d185749